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This study might not be the final word, but as someone who has taken quite a few antihistamine pills over the years, I was certainly a little concerned upon seeing hay-fever mentioned. I'm glad to see that the medication I took is a little different from the ones in the study.

From the article:

> A study has linked commonly used medicines, including over-the-counter treatments for conditions such as insomnia and hay-fever, to dementia.

> All of the types of medication in question are drugs that have an "anticholinergic" effect.

From Wikipedia: [1]

> Cetirizine /sɛˈtɪrɨziːn/ (trade names Zyrtec, Reactine).

> Unlike many other antihistamines, Cetirizine does not exhibit anticholinergic properties.

[1] http://en.wikipedia.org/wiki/Cetirizine



Let me complement your helpful answer with some details about the stuff I'm eating..

Fexofenadine (Allegra, Telfast..):

"Unlike older antihistamines, fexofenadine does not have anticholinergic activity." http://www.medscape.com/viewarticle/406437_3

Bilastine (Bilaxten):

"No anticholinergic adverse events were observed in the clinical trials.." http://en.wikipedia.org/wiki/Bilastine

"bilastine's safety profile is satisfactory, since it lacks anticholinergic effects" http://www.ncbi.nlm.nih.gov/pubmed/22149338


Thankyou, I was just about to search for Allegra, my current favourite.


As someone who doesn't respond to second-generation antihistamines, this sucks. The one I take is even listed on the "anticholinergic" Wikipedia page (Chlorpheniramine). I've always been worried about the long term effects of the drug, and limit my dosage as much as possible. I guess an allergy free life is worth some dementia risk later down the line.




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