I haven't profiled any webapps yet, but you can profile functions inside your Flask app.

First you start profiler in remote mode

    vprof -r 

and then use vprof.profiler.run function:

    profiler.run(foo, 'cmh', args=(arg1, arg2), host='localhost', port=8000)

(replace host and port if you run your webappp on another maching with address of machine you run "vprof -r" on).

This will run profiler and send stats to server in JSON format.